Complete Tips for the Best Retinol Night Cream

Checking for potential drug interactions and conflicts with current products is a good start when choosing a .

Retinol Night Cream

Consideration of skin type, the percentage of the active ingredient, any beneficial additives in the formula, season of use and time release also matters. Packaging is important, as well, because it influences the stability of the product. One of the last things people usually look when choosing Retinol Night Cream is the cost, with generic, over-the-counter products often providing very acceptable results without the high price tag of prescription-strength or name-brand choices.

Factors when Choosing Retinol

Drug Interactions

Certain drugs are not good to use with retinol. When used with tetracycline antibiotics, for example, it can cause an increase in the pressure of the fluid around the brain. Combining it with anticoagulants can reduce their effectiveness, increasing bleeding risk, and medical professionals do not recommend using it with any hepatotoxic or liver-damaging substance, because high doses of retinol by itself can hurt the liver. Many medications designed to lower cholesterol can affect retinol absorption, as can the drug, orlistat.

Products in Use

Closely related to checking drug interactions is the need to look at other products you might already be using on your skin. It is not unusual for someone to use multiple skin products on their faces for different reasons, such as exfoliating or evening out skin tone, and that’s before other items such as sunscreen. Makeup makes the number of ingredients on the skin goes up even more. For this reason, it’s a good idea to read the labels of what you already have to make sure the products won’t reduce effectiveness cause unnecessary irritation. It might be necessary to cut some items out of your routine once you start using the retinol night cream.

Skin Type

Once you’ve looked at the other products you have and the drugs you are taking, the next step is to analyze the kind of skin you have. Manufacturers often create different formulas for skin care products to accommodate various skin types, and this holds true for retinol night creams. Ones made for those with dry skin, for example, often contain humectants, which are substances that absorb water and prevent moisture loss. Those for often contain benzoyl peroxide, while those for people with oily skin frequently avoid an oil base.

Even though many people buy facial products based on a generalized concept of skin type, it’s possible for the skin to require more than one treatment. Someone can need an oil-free cream for the “T-zone” of the nose and forehead, for example, and a moisturizing one everywhere else. Some products are specifically designed for the area around the eye, as well, which tends to be thinner and more sensitive.

Active Ingredient Percentage

In general, people with sensitive or dry skin need a night cream with lower retinol percentage, but this can vary slightly based on the exact formula. The use of humectants, for example, can make a higher concentration acceptable for someone with dryness. Lower amounts also are more appropriate for people who are new to these creams. Many individuals successfully increase levels over time as their skin adjusts.

If you already are using one of these retinol night creams during the day, putting one on again at night might be too much for your skin. One option in this situation is to switch to using only the evening version. The other choice is to look for a night cream with a very low percentage of retinol.

Beneficial Additives

Part of the process of picking the right product is to see which options have additional beneficial substances. Common examples are Vitamin E, Vitamin C and alpha- and beta-hydroxy acids. These compounds usually have antioxidant properties, chemically exfoliate or provide some degree of soothing. Some, however, can treat specific problems, such as hydroquinone correcting uneven skin tone. As you age and your skin changes, you might find that you need different Retinol Night Cream ingredients.


One thing many people forget to consider when selecting the right Retinol Night Cream product is that retinol can make the skin more sensitive to the ultraviolet rays from the sun. In the summer, creams with lower concentrations can be better for this reason. In the winter, when the air tends to be more dry, switching to a product that is oil-based or which has humectants can help.

Slow-, Regular- or Fast-Release

Manufacturers often adjust their retinol night cream formulas to change how fast the retinol absorbs into the skin. Those with a slow-release design are better for those with dry or sensitive skin, because it prevents a sudden, high dose that can cause irritation. As your tolerance increases, the type of formula that works for you might shift.


Sunlight and air exposure cause retinol to break down more quickly, so toward the end of your search, you should be looking for a product that comes in an opaque bottle with a pump or a tube. Many people find that this step greatly limits their choices, because so many manufacturers use jars or other clear containers. Following the dark-and-airtight rule is beneficial, even so, because the companies that adhere to it show that they really understand what to do to make the cream effective and long-lasting, which often means an overall better formula.


Many insurance companies don’t cover the cost of skin care products, and a prescription-strength retinol night cream usually has a higher concentration of the active compound. They generally are more expensive than over-the-counter versions as a result. Their higher price tag does not guarantee a better result, however, and many individuals find that a non-prescription or more generic option works just as well. If the main ingredients and percentages are the same, picking the cheaper product typically makes good financial sense.

Retinol Night Cream

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